Ophthalmic Depot Formulations for Periocular or Suconjunctival Administration
OwnerMarklus AHLHEIM, Michael AUSBORN +2inventors
InventorsMarklus AHLHEIM, Michael AUSBORN, David BODMER, Christian SCHOCH
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Abstract
The present invention relates to ophthalmic depot formulations comprising an active agent, e.g. embedded in a pharmacologically acceptable biocompatible polymer or a lipid encapsulating agent, e.g. for periocular or subconjunctival administration.
Claims16
An ophthalmic depot formulation comprising an active agent for periocular or subconjunctival administration.
A liquid formulation comprising a dissolved pharmaceutical acceptable polymer and a dissolved or dispersed active agent which formulation upon injection forms a depot at the injection site.
A method for treating an ocular disease which comprises:
- i) providing a depot formulation comprising an active agent, and
- ii) introducing said depot formulation periocularly or subconjunctivally.
A microparticle comprising a staurosporine of formula (I), a phthalazine of formula (II) or an ophthalmically acceptable salt thereof embedded in a biocompatible pharmacologically acceptable polymer or a lipid encapsulating agent.
Dependencies are inferred from the claim text.