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US 2012/0269838 A1Published application
Carrier conjugates of il-23-peptides and their induced antibodies
AssigneePeptinov SAS
InventorsJean-François Zagury, Rojo Ratsimandresy
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Abstract
The present invention relates to a pharmaceutical composition comprising as active substance, at least one compound comprising, or consisting of, a polypeptide which comprises, or consists of, at least 11 contiguous amino acids selected from X1-S-D-I-F-X2-G-E-P-X3-L-X4-P-X5-X6-X7-X8-X9-Q-L (SEQ ID NO: 13).
Claims17
A pharmaceutical composition comprising:
- as active substance, at least one compound comprising, or consisting of, a polypeptide which comprises, or consists of, at least 11 contiguous amino acids selected from:
- a first sequence X1-S-D-I-F-X2-G-E-P-X3-L-X4-P-X5-X6-X7-X8-X9-Q-L (SEQ ID NO:
- 13), wherein:
- X1 represents G, D;
- or A
- X2 represents T or K;
- X3 represents S, P, or A;
- X4 represents L, H, or F;
- X5 represents D or N;
- X6 represents G, S, or D;
- X7 represents P or S;
- X8 represents V or M;
- X9 represents G, D, S, E, or A;
- or
- a second sequence presenting at least 90% identity with the first sequence provided that a peptide consisting of the second sequence is liable to elicit antibodies directed against IL-23;
- wherein the compound does not comprise IL23p19,
- in association with at least one pharmaceutically acceptable vehicle.
14 more elements
Dependencies are inferred from the claim text.