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US 2012/0268714 A1Published application
Non-Invasive Ocular Analyte Sensing System
AssigneeThe University of Toledo
InventorsBrent D. Cameron, Anthony Webb
Life of this patent
Estimating the term…
Abstract
A noninvasive method and apparatus for determining analyte concentration (e.g., glucose) in a subject that includes measuring light refraction from at least a portion one or more structures. One example of such structure is the subject's iris.
Claims75
(canceled)
A system for determining concentration of an ocular analyte in a subject, comprising:
- an energy source that emits at least one beam of non-collimated light, the beam being directed at one or more fiducial markers in the eye, such that at least a portion of the beam is refracted by the one or more fiducial markers;
- and,
- at least one data capturing module that receives at least one data point formed by the refracted beam, the data point comprising a perception of the one or more fiducial markers, and
- based on the perception of the one or more fiducial markers, the data capturing module correlates a level of ocular analyte in the eye with the one or more data points.
1 more element
A method for determining concentration of an ocular analyte in a subject, comprising:
- delivering an incident light to at least a portion of the subject's eye, and
- measuring refraction of the incident light with respect to a change in an index of refraction of two given media related to Equation I, (sin θ1)/(sinθ2)=η2/η1, wherein
- η1 is the refractive index of the primary (incident) medium,
- ηis the refractive index of the secondary (transmitted) medium,
- θ1 is the angle that the incident light rays take with respect to the normal, and
- θ2 is angles that the light rays take with respect to the normal.
3 more elements
An in vivo method for measuring a physiological concentration of at least one ocular analyte in an eye of a subject, comprising:
- measuring at least light refraction from one or more fiducial markers in an eye of the subject using a sequential imaging method that is accompanied with a physiological calibration process.
Dependencies are inferred from the claim text.