Back to results
US 2012/0259129 A1Published application
Process for Preparing Azabicyclic Compounds
AssigneeVertex Pharmaceuticals Incorporated
InventorsNarendra Bhalchandra Ambhaikar, Brian Richard Bear, Lev T. D. Fanning, Robert Hughes, Benjamin Littler
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process for preparing azabicyclic compounds that are useful intermediates for synthesizing pharmaceutical compounds or salts thereof.
Claims2
A process for preparing Compound 7
- or a pharmaceutically acceptable salt thereof, comprising contacting trans-4-aminocyclohexanol with Boc anhydride to produce Compound A
- contacting Compound A with methanesulfonyl chloride to produce Compound B
- contacting Compound B with trifluoroacetic acid under neat conditions to produce Compound C
- and
- contacting Compound C with hydroxide to produce Compound 7.
2 more elements
2-20. (canceled)
Dependencies are inferred from the claim text.