Formulations of acadesine
OwnerValentyn Antochshuk, Mohammed Shameem +1inventors
InventorsValentyn Antochshuk, Mohammed Shameem, Armadeep Singh Bhupender Bhalla
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Abstract
This invention provides a buffered solution comprising acadesine, as well as compositions, formulations and kits containing said solution. The solution, compositions, formulation, and kits can be used to prevent morbidity/mortality in a patient or to treat an ischaemic condition, a condition regulated by adenosine, or a condition associated with reduced blood flow to a tissue in a patient.
Claims23
1-26. (canceled)
A buffered solution comprising acadesine (5-Aminoimidazole-4-Carboxamide), or a pharmaceutically acceptable salt thereof, wherein said buffered solution has a pH of 6.0-9.6, and a headspace oxygen content of 15%, and wherein said buffered solution is substantially free of discoloration, said buffered solution being characterized by having less than or equal to (≦) 5 APHA units.
Dependencies are inferred from the claim text.