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US 2012/0258529 A1Published application
Apparatus for separating target molecules and method of separating target molecules by using the same
AssigneesKorea Advanced Institute of Science and Technology, Samsung Electronics Co., Ltd.
InventorsHee-kyun LIM, Joon-ho KIM, Myung-gwon LEE, Je-kyun PARK
Life of this patent
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Abstract
An apparatus for separating target molecules includes a plurality of protruding portions on a first sidewall of a fluid channel to control a flow of a fluid containing the target molecules, and a fluid channel portion having a variable height for separating the target molecules depending on sizes of the target molecules.
Claims13
An apparatus for separating target molecules, comprising:
- a substrate including an elastomer;
- a fluid inlet portion on the substrate and comprising at least one fluid inlet passage into which a fluid containing at least one type of target molecule is injected;
- a fluid channel portion on the substrate, in fluid connection with the fluid inlet portion, and comprising a plurality of protruding portions on a first sidewall thereof, wherein the protruding portions control a flow of the fluid, and a height of the fluid channel portion is variable so that the target molecules are separated based on a size of the target molecules;
- and
- a fluid outlet portion on the substrate, in fluid connection with the fluid channel portion, and comprising at least one fluid outlet passage through which the separated target molecules are discharged.
2 more elements
A method of separating target molecules, comprising:
- injecting a fluid containing at least one type of target molecules into a fluid inlet portion of an apparatus,
- separating the target molecules depending on a size of the target molecules by controlling a flow of the fluid with a fluid channel portion of the apparatus, which is in fluid connection with the fluid inlet portion, and
- discharging the fluid containing the separated target molecules through a fluid outlet portion of the apparatus, which is in fluid connection with the fluid channel,
- wherein the apparatus comprises:
- a substrate including an elastomer,
- the fluid inlet portion on the substrate and comprising at least one fluid inlet passage,
- the fluid channel portion on the substrate, comprising a plurality of protruding portions on a first sidewall thereof and having a variable height, and
- the fluid outlet portion on the substrate and comprising at least one fluid outlet passage.
5 more elements
An apparatus for separating target molecules, comprising:
- a fluid inlet passage into which a fluid containing at least one type of target molecule is injected;
- a fluid outlet passage through which separated target molecules are discharged and in fluid connection with the fluid channel;
- and
- a fluid channel between the fluid inlet passage and the fluid outlet passage, through which the fluid flows in a flow direction and in fluid connection with the fluid inlet passage and the fluid outlet passage, the fluid channel comprising:
- a first channel portion having a first width perpendicular to the flow direction,
- a second channel portion having a second width perpendicular to the flow direction and smaller than the first width, and
- a plurality of protruding portions which are extended from a sidewall of the fluid channel and define the first and second channel portions;
- and
- wherein
- a height of the second channel portion is variable and is less than the second width.
7 more elements
Dependencies are inferred from the claim text.