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AssigneeKane Biotech Inc.
InventorsSrinivasa MADHYASTHA, Nanda Yakandawala, Purushottam V. Gawande, Karen Lovetri, Jeffrey B. Kaplan, Daniel Rhoads, Lasha Gogokhia
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The present invention provides compositions comprising an antibiofilm enzyme, a soluble β-N-acetylglucosaminidase similar to the dspB gene (DispersinB®), and an antimicrobial for preventing growth and proliferation of biofilm-embedded microorganisms in acute and chronic wounds, and methods of treatment. The invention further provides methods for preparing medical devices, and in particular, wound care devices using soluble β-N-acetylglucosaminidase based antimicrobial compositions.
A composition for inhibiting biofilm-embedded microorganisms comprising:
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A method of inhibiting biofilm-embedded microorganisms comprising administering an effective amount of (a) amino acids 21-381 of SEQ ID NO:2, an active fragment or variant thereof that disperses a biofilm;
Dependencies are inferred from the claim text.