Methods affecting markers in patients having vascular disease
AssigneeTyco Healthcare Group LP
InventorJohn B. Simpson
Life of this patent
Estimating the term…
Abstract
Marker levels and forms can be modulated in patients having vascular disease when sufficient vascular tissue is removed. The markers can be, e.g., from tissue, blood or lymph. The markers are typically involved in molecular pathways which are in turn modulated. Atherectomy catheters are used for accomplishing sufficient removal of vascular tissue to effect the modulations.
Claims24
A method of modulating level of a marker in a patient having vascular disease comprising the steps of:
- determining a first level of a marker in the patient;
- removing sufficient vascular tissue from said patient to modulate level of said marker;
- and
- determining a second level of the marker after removing the vascular tissue.
A method of modulating level of a marker in a patient having vascular disease comprising the steps of:
- determining a first level of a marker in the patient;
- introducing an atherectomy catheter percutaneously in the patient and directing the catheter to a first site in a vascular lumen containing vascular tissue;
- removing sufficient vascular tissue from the vascular lumen to modulate level of said marker;
- and
- determining a second level of the marker after removing the vascular tissue.
A method of modifying a marker in a patient having vascular disease comprising the steps of:
- determining a first form of a marker in the patient;
- removing vascular tissue sufficient to effect a modification of the marker to a second form;
- and
- determining the second form of the marker in the patient.
Dependencies are inferred from the claim text.