Devices and processes for nucleic acid extraction

A device comprising:

• (i) a body member having a plurality of external surfaces and fabricated to contain a continuous fluid pathway therethrough, the pathway comprising:
• a first port;
• a second port;
• and
• a binding channel intermediate and in fluid communication with the first port and the second port, wherein the binding channel is open to one of the external surfaces of the body member;
• and
• (ii) a glass member affixed to said one of the external surfaces of the body member to provide a first unmodified flat glass surface in fluid communication with the binding channel, wherein the binding channel and glass member define a binding chamber effective for binding a heterogeneous population of nucleic acids and wherein the fluid pathway is essentially free of nucleic acid-specific binding sites.