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US 2012/0237511 A1Published application
Fgfr1 extracellular domain combination therapies
AssigneeFive Prime Therapeutics, Inc.
InventorsLi Long, Thomas Brennan
Life of this patent
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AssigneeFive Prime Therapeutics, Inc.
InventorsLi Long, Thomas Brennan
Estimating the term…
Methods of treating cancer comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule in combination with at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are provided. Dosage packs comprising an FGFR1 ECD and/or an FGFR1 ECD fusion molecule and/or at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, and bevacizumab are also provided. In some embodiments, a dosage pack comprises instructions for administering FGFR1 ECD and/or FGFR1 ECD fusion molecule with at least one additional therapeutic agent.
A method of treating cancer comprising administering to a subject a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) fusion molecule and at least one additional therapeutic agent selected from docetaxel, paclitaxel, vincristine, carboplatin, cisplatin, oxaliplatin, doxorubicin, 5-fluorouracil (5-FU), leucovorin, pemetrexed, etoposide, topotecan, a VEGF antagonist, a VEGF trap, an anti-VEGF antibody, and bevacizumab, wherein the FGFR1 ECD fusion molecule comprises an FGFR1 ECD and a fusion partner.
A dosage pack comprising at least one component selected from:
Dependencies are inferred from the claim text.