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US 2012/0235061 A1Published application
Lighting design of high quality biomedical devices
AssigneeLumencor, Inc.
InventorsClaudia B. Jaffe, Steven M. Jaffe, Arlie R. Conner
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Abstract
The invention relates to a plurality of light sources to power a variety of applications including microarray readers, microplate scanners, microfluidic analyzers, sensors, sequencers, Q-PCR and a host of other bioanalytical tools that drive today's commercial, academic and clinical biotech labs.
Claims20
A method for analyzing a sample comprising:
- (a) pumping at least one luminescent light pipe to generate at least a first excitation light and driving at least one LED light source to generate at least a second excitation light;
- (b) directing the at least first excitation light and the at least second excitation light onto a single optical axis using one or more dichroic mirrors to create an excitation light beam;
- (c) directing the excitation light beam onto the sample;
- (d) detecting light from the sample with one or more detectors;
- and
- (e) switching at a frequency no less than 2 kHz to modulate the excitation light beam.
3 more elements
A solid-state light engine adapted to analyze a sample having one or more tags, wherein the solid state light engine comprises:
- a light pipe coupled to a solid state light source, and a plurality of LED light sources, wherein the light pipe and the plurality of LED light sources are adapted to produce a plurality of beams of excitation light having a plurality of colors;
- wherein the solid state light source and the plurality of LED light sources are switchable at a frequency of 2 kHz or more to modulate the plurality of beams of excitation light;
- a plurality of dichroic mirrors positioned to direct the plurality of beams of excitation light onto a single optical axis;
- and
- wherein the plurality of beams of excitation light are adapted to selectively detect the one of more tags within the sample.
2 more elements
A solid-state light engine comprising:
- a plurality of LED light sources, and a luminescent light pipe pumped by a solid state light source, wherein the luminescent light pipe and the plurality of LED light sources are adapted to produce a plurality of beams of excitation light having a plurality of colors;
- wherein the solid state light source and the plurality of LED light sources are switchable at a frequency of 2 kHz or more to modulate the plurality of beams of excitation light;
- a plurality of dichroic elements positioned to direct the plurality of beams of excitation light onto a single optical axis;
- and
- relay optics adapted to direct the plurality of beams of excitation light from the single optical axis to a sample.
2 more elements
Dependencies are inferred from the claim text.