Method of treating an anxiety disorder

The method of treating an anxiety disorder according to claim 25, wherein the adenosine A2A receptor antagonist is represented by formula (II):

• wherein R11 represents substituted or unsubstituted aryl, or a substituted or unsubstituted heterocyclic group;
• R12 represents hydrogen, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, or a substituted or unsubstituted heterocyclic group;
• R13 represents hydrogen, halogen or —WR14 (in which W represents —O— or —S—;
• and R14 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, or a substituted or unsubstituted heterocyclic group);
• and
• Q1 represents hydrogen or 3,4-dimethoxybenzyl,
• or a pharmaceutically acceptable salt thereof.

The method of treating an anxiety disorder according to claim 25, wherein the adenosine A2A receptor antagonist is represented by formula (III):

• wherein R11A represents substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R12A represents hydrogen, halogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• m1 and n1 are independently an integer of 0 to 4;
• Q1A represents hydrogen or 3,4-dimethoxybenzyl;
• R15 represents hydrogen, substituted or unsubstituted aryl, a substituted or unsubstituted heterocyalic group, or —CR17R18R19 (in which R17, R18 and R19 independently represent hydrogen, hydroxy, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, substituted or unsubstituted aryl, or a substituted or unsubstituted heterocyalic group;
• or R18 and R19 are combined together with an adjacent carbon atom to form a substituted or unsubstituted carbon ring);
• and
• R16 represents hydrogen, halogen, hydroxy, or substituted or unsubstituted lower alkyl,
• or a pharmaceutically acceptable salt thereof.

The method of treating an anxiety disorder according to claim 25, wherein the adenosine A2A receptor antagonist is a represented by formula (XII):

• R54 represents substituted or unsubstituted aryl, substituted or unsubstituted cycloalkenyl, or substituted or unsubstituted heteroaryl;
• W4 represents a single bond or —C(═O)—;
• and
• R55 represents substituted or unsubstituted lower alkyl,
• or a pharmaceutically acceptable salt thereof.

The method of treating an anxiety disorder according to claim 25, wherein the adenosine A2A receptor antagonist is represented by formula (XVIII):

• R81 represents substituted or unsubstituted aryl, substituted or unsubstituted cycloalkenyl, or substituted or unsubstituted heteroaryl;
• W6 represents a single bond or —C(═O)—;
• and
• R82 represents substituted or unsubstituted lower alkyl,
• or a pharmaceutically acceptable salt thereof.