US 2012/0231533 A1 · DEVICE AND METHOD FOR THE STUDY OF CELL AND TISSUE FUNCTION

Device and method for the study of cell and tissue function

OwnerMark R. Holl, Deirdre R. Meldrum +14inventors

InventorsMark R. Holl, Deirdre R. Meldrum, A. Cody Youngbull, Haixin Zhu, Jeff Houkal, Yanqing Tian, Shashanka Ashili, Laimonas Kelbauskas, Roger Johnson, Shih-hui Chao, Peter Wiktor, Alex Jen, Lloyd Burgess, Sarah McQuaid, Ai Brunner, Peter Kahn

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Abstract

A chamber device for analyzing living cell(s). The chamber device includes a base and a lid that when reversibly pressed closed create a chamber. The base is configured with an optically transparent well to contain at least one cell. The lid has a breadth greater than the base and is configured to contain at least one sensor. The lid is further configured with a lip that when pressed between the lid and the base creates an impermeable seal. The base and the lid are configured so that, when closed and in use, the sensor remains spatially apart from the at least one cell.

Claims36

Dependent claims

A chamber device for analyzing living cell(s) comprising:

a base and a lid that when reversibly pressed closed create a chamber;
the base configured with an optically transparent well to contain at least one cell;
the lid having a breadth greater than the base, and configured to contain at least one sensor;
wherein the lid is further configured with a lip that when pressed between the lid and the base creates an impermeable seal;
and
wherein the base and the lid are configured so that, when closed and in use, the sensor remains spatially apart from the at least one cell.

3 more elements

Dependencies are inferred from the claim text.