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AssigneesThe Board of Trustees of the University of Illinois, Pier Pharmaceuticals
InventorsDavid Carley, Kenton Fedde, John KOLENG, Peter LETENDRE
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The present invention provides a medicament which results in delivery of a therapeutic level of one or more cannabinoids during a clinically relevant therapeutic window. The therapeutic window is a longer window than provided by an immediate release medicament such as Marinol containing an equivalent amount of the cannabinoid. Oral administration of the present compositions provides therapeutic dosing while maintaining safe, side effect sparing, levels of a cannabinoid. The present invention also provides methods of treating cannabinoid-sensitive disorders.
A medicament comprising a cannabinoid partitioned in an immediate release compartment and in a delayed release compartment wherein the cannabinoid is present in an amount of about 1 to about 75 mg and optionally wherein when administered to a human subject, the medicament provides a PK Profile of any one of PK Profiles 1-20.
Dependencies are inferred from the claim text.