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US 2012/0231049 A1Published application
Freeze-Thaw Method For Modifying Stent Coating
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsSyed F.A. Hossainy, Gordon Stewart, Benjamyn Serna, Lothar W. Kleiner
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Abstract
Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
Claims10
A method comprising:
- (a) preparing a coating composition comprising one or more polymers, one or more solvents and optionally one or more therapeutic agents;
- (b) applying the coating composition onto a medical device to form a wet coating layer;
- and
- (c) subjecting the wet coating layer to a freeze-thaw cycle.
1 more element
Dependencies are inferred from the claim text.