Cysteine variants of interleukin-11 and methods of use thereof
AssigneeBolder Biotechnology, Inc.
InventorGeorge N. Cox, III
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Abstract
Disclosed are cysteine variants of interleukin-11 (IL-11) and methods of making and using such proteins in therapeutic applications.
Claims25
A method to treat an animal with a disease or condition that can be treated by wild-type interleukin-11 (IL-11), to stimulate platelet production in an animal, or to accelerate an animal's recovery from thrombocytopenia, comprising administering to the animal an interleukin-11 (IL-11) cysteine mutein, wherein the mutein has biological activity in vitro as measured by proliferation of a cell line that proliferates in response to IL-11.
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Dependencies are inferred from the claim text.