Nitric oxide releasing particles for oral care applications
OwnerNathan Staskoinventor
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Abstract
The present invention provides an oral care composition comprising a nitric oxide releasing particle and an orally-acceptable carrier. The nitric oxide releasing particle comprises at least one nitric oxide donor. Another aspect of the present invention provides a device for oral care comprising a nitric oxide releasing particle, wherein the device is configured to expose a targeted site in an oral cavity of a subject to nitric oxide. The present invention also provides methods and uses of providing oral health benefits by using the oral care compositions or devices as described above.
Claims20
A device comprising at least two separate phases, wherein a first phase comprises a nitric oxide releasing particle comprising a diazeniumdiolate and a second phase regulates the release of nitric oxide, and wherein the device is configured to admix the two separate phases upon administration.
A device comprising at least two separate phases, wherein a first phase comprises a nitric oxide releasing particle comprising a diazeniumdiolate and has a basic pH and a second phase regulates the release of nitric oxide and has a pH that is different than the pH of the first phase, and wherein the device is configured to admix the two separate phases upon administration to provide a desired kinetics of nitric oxide release.
Dependencies are inferred from the claim text.