Novel injectable chitosan mixtures forming hydrogels
AssigneeChi2Gel Ltd.
InventorsNoah Ben-Shalom, Zvi Nevo, Abraham Patchornik, Dror Robinson
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AssigneeChi2Gel Ltd.
InventorsNoah Ben-Shalom, Zvi Nevo, Abraham Patchornik, Dror Robinson
Estimating the term…
A chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70% is disclosed. Further disclosed is a chitosan composition which forms a hydrogel at near physiological pH and 37° C., comprising at least one type of chitosan having a degree of deacetylation of at least about 70% and a molecular weight of from 10-4000 kDa, and at least one type of a chitosan having a molecular weight of from 200-20000 Da. Further disclosed are methods of preparation and uses of the chitosan compositions.
A chitosan composition which forms a hydrogel at near physiological pH and at 37° C., comprising at least one type of chitosan having a degree of acetylation in the range of from about 30% to about 60%, and at least one type of chitosan having a degree of deacetylation of at least about 70%, the composition being in a form of an aqueous solution.
A process for preparing a stable pH-dependant and temperature-dependant chitosan hydrogel composition comprised of at least one highly acetylated chitosan having a degree of acetylation of from about 30 to about 60%, and at least one highly deacetylated chitosan having a degree of deacetylation of from about 70%, the process comprising:
A chitosan composition which forms a hydrogel at near physiological pH and at 37° C., the composition comprising at least one type of a highly deacetylated chitosan having a molecular weight of from 10-4000 kDa and a degree of deacetylation of at least 70%, and at least one type of a chitosan having a molecular weight of from 200-20000 Da, the composition being in a form of an aqueous solution.
Dependencies are inferred from the claim text.