Method of delivering material or stimulus to a biological subject
AssigneeVaxxas Pty Limited
InventorMark Anthony Fernance Kendall
Life of this patent
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Abstract
A device for delivery of material or stimulus to targets within a body to produce a desired response, the targets being at least one of cells of interest, cell organelles of interest and cell nuclei of interest. The device includes a number of projections for penetrating a body surface, with the number of projections being selected to produce a desired response, and the number being at least 500. A spacing between projections is also at least partially determined based on an arrangement of the targets within the body.
Claims34
1-45. (canceled)
A method of delivering material or stimulus to a biological subject, the method comprising applying a device to the biological subject, the device comprising:
- a) a base;
- and
- b) projections extending from the base, wherein each projection comprises a tip for penetrating a surface of the biological subject, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- and
- iv) projections are separated by a spacing of between 10 μm and 200 μm.
A method of delivering vaccine to a biological subject to produce an immunological response, the method comprising applying a device to the biological subject, the device comprising:
- a) a base;
- and
- b) projections extending from the base, wherein each projection comprises a tip for penetrating a surface of the biological subject, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- iv) projections are separated by a spacing of between 10 μm and 200 μm;
- and
- v) one or more of the projections are at least partially coated with a vaccine.
A method for delivering material to a biological subject, the method comprising applying a device to the biological subject, the device comprising:
- a) a base;
- and
- b) projections extending from the base, wherein each projection comprises a tip for penetrating a surface of the biological subject, and wherein at least part of at least some of the projections is coated, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- and
- iv) projections are separated by a spacing of between 10 μm and 200 μm.
A method for delivering stimulus to a biological subject, the method comprising applying a device to the biological subject, the device comprising:
- a) a base;
- and
- b) projections extending from the base, wherein each projection comprises a tip for penetrating a surface of the biological surface, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- and
- iv) projections are separated by a spacing of between 10 μm and 200 μm.
A method of treating a biological subject, the method comprising applying a skin penetrating device to a biological subject, the device comprising:
- a) a base;
- and
- b) a number of projections extending from the base, wherein the projections are arranged in an array, and wherein each projection comprises a tip for penetrating a surface of the biological subject, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- and
- iv) projections are separated by a spacing of between 10 μm and 200 μm.
A method of treating a biological subject, the method comprising using a device for delivery of material or stimulus biological subject, the device comprising:
- a) a base;
- and
- b) projections extending from the base, wherein each projection comprises a tip for penetrating a surface of the biological subject, and wherein:
- i) the number of projections is at least 500;
- ii) each projection has a length of between 200 μm and 1000 μm;
- iii) each projection has a base width of between 5 μm and 50 μm;
- and
- iv) projections are separated by a spacing of between 10 μm and 200 μm.
A method of treating a subject, the method comprising using a device for delivery of material or stimulus to targets within the subject's body to produce a desired response, the targets being at least one of cells of interest, cell organelles of interest and cell nuclei of interest, the device comprising a number of projections for penetrating a body surface, and wherein:
- a) the number of projections is selected to produce a desired response, the number being at least 500;
- and,
- b) a spacing between projections is at least partially determined based on an arrangement of the targets within the body.
Dependencies are inferred from the claim text.