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US 2012/0083457 A1Published application
Bortezomib Formulations
AssigneeAPP Pharmaceuticals, LLC.
InventorsArunya Usayapant, David Bowman
Life of this patent
Estimating the term…
Abstract
A bortezomib composition includes bortezomib and boric acid in a mass ratio of boric acid to bortezomib is from 1:1 to 10:1. The composition is a solid, and may be prepared by forming a liquid mixture including a solvent, bortezomib and boric acid, and lyophilizing the liquid mixture.
Claims23
A composition, comprising:
- bortezomib, and
- boric acid;
- where the composition is a solid, and
- the mass ratio of boric acid to bortezomib is from 1:1 to 10:1.
1 more element
19-20. (canceled)
A method of making a solid composition, comprising:
- forming a liquid mixture comprising a solvent, bortezomib and boric acid, and
- lyophilizing the liquid mixture.
22-30. (canceled)
A composition, formed by a method comprising:
- forming a liquid mixture comprising a solvent, bortezomib and boric acid,
- where the mass ratio of boric acid to bortezomib in the liquid mixture is from 1:1 to 10:1, and
- lyophilizing the liquid mixture to form a solid composition.
32-45. (canceled)
Dependencies are inferred from the claim text.