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US 2012/0083422 A1Published application
Glioblastoma Biomarkers, and Methods and Compositions
OwnerClaudius Mueller, Lance Liotta +2inventors
InventorsClaudius Mueller, Lance Liotta, Emanuel Petricoin, Virginia Espina
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Abstract
Glioblastoma multiforme biomarkers, methods, and compositions are provided. Methods of selecting a treatment for a patient with a brain neoplasm, including Glioblastoma multiforme, are provided. Methods of treating a patient at risk for Glioblastoma multiforme are provided.
Claims2
A method of selecting a treatment for a patient with a brain neoplasm comprising:
- a. incubating a brain tissue sample from said patient with one or more candidate therapeutics;
- b. stopping the incubation and applying a fixative to the stopped incubation;
- c. determining the activation status of at least one protein;
- and
- d. using the determination to select a treatment that advantageously impacts brain tissue.
2 more elements
2-22. (canceled)
Dependencies are inferred from the claim text.