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US 2012/0059597 A1Published application
Computational methods and systems for treatment in relation to modulation of CYP450 enzyme activity
AssigneeSearete LLC, a limited liability corporation of the State of Delaware
InventorsMahalaxmi Gita Bangera, Roderick A. Hyde, Muriel Y. Ishikawa, Elizabeth A. Sweeney, Lowell L. Wood, JR., Victoria Y.H. Wood
Life of this patent
Estimating the term…
Abstract
Methods and systems such as those described herein include accepting input, identifying CYP450-family enzymes, identifying at least one modulator of an enzyme, and communicating one or more treatments to a system user.
Claims46
A method comprising:
- accepting input that specifies an individual;
- accepting input that specifies at least one environmental exposure of the individual;
- identifying at least one toxin associated with the at least one environmental exposure;
- identifying at least one CYP450-family enzyme associated with metabolism of one or more of the at least one toxin;
- identifying at least one modulator of one or more of the at least one CYP450-family enzyme;
- and
- invoking circuitry for communicating one or more treatment to a system user, wherein the one or more treatment includes the at least one modulator of one or more of the at least one CYP450-family enzyme.
4 more elements
-23. (canceled)
A system comprising:
- circuitry for accepting input that specifies an individual;
- circuitry for accepting input that specifies at least one environmental exposure of the individual;
- circuitry for identifying at least one toxin associated with the at least one environmental exposure;
- circuitry for identifying at least one CYP450-family enzyme associated with metabolism of one or more of the at least one toxin;
- circuitry for identifying at least one modulator of one or more of the at least one CYP450-family enzyme;
- and
- circuitry for communicating one or more treatment to a system user, wherein the one or more treatment includes the at least one modulator of one or more of the at least one CYP450-family enzyme.
4 more elements
-46. (canceled)
A method, comprising:
- accepting input relating to microbial infection associated with an individual;
- identifying at least one statin therapy, wherein the at least one statin therapy is associated with a reduction in the microbial infection;
- identifying at least one CYP450-family enzyme, wherein the at least one CYP450-family enzyme is associated with metabolism of the at least one statin therapy;
- identifying at least one modulator of the at least one CYP450-family enzyme;
- and
- invoking circuitry for communicating at least one treatment to a system user, wherein the at least one treatment includes the at least one statin therapy and the at least one modulator.
3 more elements
-55. (canceled)
-60. (canceled)
-70. (canceled)
A system, comprising:
- circuitry for accepting input relating to microbial infection associated with an individual;
- circuitry for identifying at least one statin therapy, wherein the at least one statin therapy is associated with a reduction in the microbial infection;
- circuitry for identifying at least one CYP450-family enzyme, wherein the at least one CYP450-family enzyme is associated with metabolism of the at least one statin therapy;
- circuitry for identifying at least one modulator of the at least one CYP450-family enzyme;
- and
- circuitry for communicating at least one treatment to a system user, wherein the at least one treatment includes the at least one statin therapy and the at least one modulator.
3 more elements
-79. (canceled)
-84. (canceled)
-96. (canceled)
Dependencies are inferred from the claim text.