Method for suppressing cell growth

A method for preparing a virus-resistant transformant comprising the steps of:

• introducing DNA containing regions coding for a promoter of an interferon regulatory factor gene, an interferon gene promoter, an interferon-stimulated response promoter, or a phage shock protein (psp) promoter, and an arbitrary protein into a target cell to obtain a transformant;
• wherein the region of DNA contains a three-nucleotide chain, and
• the three-nucleotide chain is selected from among codons specifying at least a portion of the amino acids constituting the protein, and is complementary to at least a portion of codons having a use frequency of 0.2 or lower in the target cell.

A vector containing DNA that contains a region coding for an arbitrary protein in a state that can be expressed,

• wherein the region of the DNA contains a three-nucleotide chain;
• and
• the three-nucleotide chain is selected from among codons specifying at least a portion of the amino acids constituting the protein, and is complementary to at least a portion of the codons having a use frequency of 0.2 or lower in a target cell.

A vector into which DNA that contains a region coding for an arbitrary protein can be inserted,

• wherein the region of DNA contains a three-nucleotide chain;
• and
• the three-nucleotide chain is selected from among codons specifying at least a portion of the amino acids constituting the protein, and is complementary to at least a portion of the codons having a use frequency of 0.2 or lower in a target cell.