Back to results
US 2011/0300172 A1Published application
Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis
AssigneeCardioVax, LLC
InventorsJan NILSSON, Goran K. Hansson, Jan Holmgren
Life of this patent
Estimating the term…
Abstract
A fusion protein comprising an antigenic fragment of apoB-100 and a suitable carrier and related compositions methods and systems.
Claims20
A fusion protein comprising
- an antigenic fragment of apoB-100 protein or a derivative thereof and a protein carrier,
- wherein the antigenic fragment and the protein carrier are comprised in the fusion protein in a 1:1 fragment:carrier molar ratio;
- and
- wherein the fusion protein is capable of inducing antigen specific regulatory T cells, the antigen specific regulatory T cells being specific for the antigenic fragment of apoB-100.
1 more element
A method to produce a fusion protein, the method comprising
- attaching an antigenic fragment of apoB-100 or a derivative thereof with a suitable protein carrier in a 1:1 fragment:carrier molar ratio to provide a fusion protein capable of inducing antigen specific regulatory T cells,
- the antigen specific regulatory T cells being specific for the fragment of apoB-100 or the derivative thereof.
Dependencies are inferred from the claim text.