The method for execution in a printing press (01) comprising a plurality of printing couples (03), wherein at least two different inks are applied by these printing couples (03) to the same print substrate (02) along the transport path thereof through the printing press (01) in order to produce the same printed image, wherein an ink controller (24) calculates how many additional printed images must be imprinted by each of the respective printing couples (03) involved in producing these printed images, following an at least zonal disengagement or interruption of an ink feed in each of these printing couples (03), with a volume of ink remaining on the print substrate side in each respective printing couple (03), until an area coverage produced in each of the printing couples (03) with the volume of ink transferred to the print substrate (02) equals a target value for area coverage, wherein the area coverage is produced in each case by a volume of ink transferred to the print substrate (02) by an inking unit (04) belonging to the respective printing couple (03), wherein in the respective printing couple (03), at least one printing forme, inked by the inking unit (04) for the purpose of executing a previous printing process, is replaced by another printing forme provided for the purpose of executing the subsequent printing process only after the area coverage produced on the print substrate (02) with the volume of ink remaining in the relevant inking unit (04) equals the target value for area coverage, wherein a changeover of the printing press from the printing process currently running in said printing press to a subsequent printing process is carried out in a control process that runs automatically, characterized in that in the subsequent printing process, the same ink is transferred to the print substrate (02) from each of the inking units (04) involved in executing the previous printing process as in the previous printing process, wherein the respective target value for the area coverage is equal in each case to the area coverage predefined for a pre-print run of the subsequent printing process, wherein the control process executed by the ink controller (24) is carried out taking into consideration the respective predefined target value for the area coverage to be adjusted.