Adamantane Derivatives Of Aza-Crown Ethers And Their Use In Treatment Of Tumor

A pharmaceutical composition for treatment of cancer and tumors, comprising:

• a compound having general formula I:
• wherein R and R′ are selected from the group comprising
• provided that R and R′ cannot simultaneously be H;
• and
• n is an integer from 1 to 4;
• and pharmaceutically acceptable salts thereof.

A pharmaceutical composition for treatment of cancer and tumors, comprising:

• a compound having general formula II
• wherein
• R″ is selected from the group comprising:
• and n is an integer from 1 to 4,
• and pharmaceutically acceptable salts thereof.

Use of a compound having general formula I:

• wherein R and R′ are selected from the group comprising
• provided that R and R′ cannot simultaneously be H;
• and
• n is an integer from 1 to 4;
• or pharmaceutically acceptable salts thereof
• in the production of a medicament for treatment of tumors.

Use of a compound having general formula II

• wherein
• R″ is selected from the group comprising:
• and n is an integer from 1 to 4,
• or pharmaceutically acceptable salts thereof.
• in the production of a medicament for treatment of tumors.