Substituted piperidine spiro pyrrolidinone and piperidinone, preparation and therapeutic use thereof

A compound of formula (I):

• wherein
• m is 1 or 2;
• n is 1 or 2;
• p is 1 or 2;
• R1 is hydrogen, (C1-C4)alkyl, CF3, or (C1-C4)alkoxy-(C1-C4)alkyl;
• R2 is hydrogen, halogen, (C1-C4)alkyl or CF3;
• and
• R3 is hydrogen, (C1-C4)alkyl, (C1-C6)alkyloxycarbonyl, (C3-C7)cycloalkyl(C1-C6)alkyl, substituted or unsubstituted heterocycle, substituted or unsubstituted heterocycloalkyl(C1-C6)alkyl, substituted or unsubstituted 5- or 6-membered ring heteroaryl(C1-C6)alkyl, substituted or unsubstituted benzyl, (C1-C4)alkoxymethylcarbonyl, substituted or unsubstituted (C3-C7)cycloalkanecarbonyl, substituted or unsubstituted benzylcarbonyl, substituted or unsubstituted (C6-C10)arylcarbonyl, substituted or unsubstituted 5 or 6-membered ring heteroarylcarbonyl, substituted or unsubstituted heterocyclecarbonyl, substituted or unsubstituted benzenesulfonyl, wherein the substituents are selected from halogen, trifluoromethoxy, (C1-C4)alkoxy, (C1-C4)alkyl and CF3;
• or a salt, enantiomer or diastereomer thereof.