Antibacterial combination therapy for the treatment of gram positive bacterial infections
AssigneeE-Therapeutics PLC
InventorsMalcolm Philip Young, Catherine Mary Thomas
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Abstract
There is described a composition comprising a therapeutically active imidazole, and derivatives thereof, and an agent active on a bacterial cell surface selected from the group consisting of one or more of colistin, nisin, D-cycloserine, fosfomycin, fosfomycin trometamol, fosfomycin disodium and polymixin B, and derivatives thereof.
Claims36
A composition comprising a therapeutically active imidazole, and derivatives thereof, and an agent active on a bacterial cell surface selected from the group consisting of one or more of colistin, nisin, D-cycloserine, fosfomycin and polymixin B, and derivatives thereof.
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A method of treating a subject suffering from an infection contributed to or caused by gram-positive bacteria, said method comprising the step of administering an effective amount of a therapeutically active imidazole, and derivatives thereof, with an agent active on a bacterial cell surface selected from the group consisting of one or more of colistin, nisin, D-cycloserine, fosfomycin and polymixin B, and derivatives thereof, separately, simultaneously or sequentially.
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Dependencies are inferred from the claim text.