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AssigneeCmed Technologies Ltd.
InventorsZhong Chen, Ning Liu, Huawei Yang, Hongtao Zhang, Yuye Yang, Yuyang Hu, Sheng Wang, Qingmei Ma
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The present invention discloses using SPR technology to simultaneously and qualitatively detect different HPV genotypes. It also discloses an efficient formula to make a mixed SAM that can greatly enhance the immobilization ability of the metal surface in SPR based techniques, which is good for the immobilization of HPV specific DNA probes used for the detection of different HPV genotypes.
An improved SPR biosensor chip for simultaneous detection of multiple HPV genotypes prepared by forming a linking layer on the surface of a metal film on a glass chip and immobilizing of multiple HPV probes on the surface of the linking layer.
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