Water insoluble polymer: indigestible water-soluble polysaccharide film coatings for colon targeting
AssigneeRoquette Freres
InventorsOlaf Haeusler, Daniel Wils, Juergen Siepmann, Youness Karrout
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Abstract
A controlled release pharmaceutical dosage form for controlled release of an active ingredient, includes an active ingredient coated by a polymeric mixture of: at least a water insoluble polymer; and at least an indigestible water-soluble oligosaccharide. The use and method of making the same are also described.
Claims16
A controlled release delivery dosage form for controlled release of an active ingredient, comprising an active ingredient coated by a polymeric mixture of:
- at least a water insoluble polymer and
- at least an indigestible water-soluble polysaccharide.
A method for preparing a controlled release delivery dosage form for controlled release of an active ingredient in the colon of patients having a colonic microflora imbalance or in the colon of healthy subjects, said method comprising:
- forming a polymeric mixture of:
- at least one water insoluble polymer and
- at least an indigestible water-soluble polysaccharides,
- coating said active ingredient by the polymeric mixture.
Method of using a colon targeting coating preparation comprising a water insoluble polymer and an indigestible water-soluble polysaccharides, in the manufacture of a medicament for stimulating the growth and/or activity of bacteria in the digestive system.
Dependencies are inferred from the claim text.