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AssigneeMillipore Corporation
InventorsMasaharu Mabuchi, Hiroko Kimura, Marc Emerick, Phillip Clark, Kurt Greenizen
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The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.
A device for conducting immunoassays comprising a holder formed of a material selected from the group consisting of plastic and paper, the holder having a first portion and second portion, a central opening area formed in each of the first and second portion the opening of each portion being aligned with the other opening of the opposite portion when the first portion and second portions of the holder are adjacent each other in a closed position, a porous support covers opening of the first portion and a flow distributor covers the opening of the second portion wherein the holder has a means for releasably securing the first and second portions to each other.
A device for conducting vacuum assisted immunoassays comprising a vacuum manifold and a holder formed of a material selected from the group consisting of plastic and paper, the holder having a first portion and second portion, a central opening area formed in each of the first and second portion the opening of each portion being aligned with the other opening of the opposite portion when the first portion and second portions of the holder are adjacent each other in a closed position, a porous support covers opening of the first portion and a flow distributor covers the opening of the second portion wherein the holder has a means for releasably securing the first and second portions to each other.
Dependencies are inferred from the claim text.