Gene of porcine alpha-si casein, a promoter of the same and use thereof
AssigneeCho-A Pharm Co., Ltd.
InventorsMyeong Goo Yeo, Sung-Jo Kang, Jong Deok Ahn
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Abstract
The present invention relates to a porcine alpha-S1-casein gene, a porcine alpha-S1-casein gene promoter, an expression comprising the same promoter, and a method for the production of a target protein using the same expression vector. The promoter of the present invention facilitates the mammary gland-specific expression of the target protein. Accordingly, an animal transformed with the promoter secretes the target protein in milk at high concentration, and thus can be advantageously used for the production of useful proteins.
Claims25
An isolated porcine alpha-S1-casein gene having a sequence of nucleotides set forth as SEQ ID NO:
- 1, which comprises a promoter and a 3′ UTR region.
An isolated porcine alpha-S1-casein gene promoter, comprising a sequence of nucleotides set forth as SEQ ID NO:
- 2.
An expression vector, comprising one or more sequences of nucleotides selected from among the sequences set forth as SEQ ID NO:
- 2, SEQ ID NO:
- 3 and SEQ ID NO:
- 4.
(canceled)
Dependencies are inferred from the claim text.