Pharmaceutical-coated medical products, the production thereof and the use thereof
AssigneeInvatec Technology Center GmbH
InventorsBruno Scheller, Ulrich Speck
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Abstract
This present invention concerns a new combination of balloon catheters and formulations containing active substances that adhere to the surface of the balloon membrane. Furthermore the present invention concerns coating processes for the manufacture of these balloon catheters as well as their use in the treatment and prophylaxis of vascular diseases.
Claims37
A balloon catheter including a catheter balloon with a hydrophilic or hydrophilised balloon membrane where the balloon membrane is coated with at least one active substance lying open on the surface of said catheter balloon the balloon membrane coated in such a way that the at least one active substance is immediately released when the catheter balloon is expanded.
A balloon catheter with at least one active substance that lies open on the surface the substance being immediately released when the catheter balloon is expanded and where the radius of the catheter balloon is increased by more than 15%, following complete unfolding of the catheter balloon by means of a pressure increase applied inside the catheter balloon.
A process for the coating of catheter balloons including the following stages:
- a) preparing a catheter balloon,
- b) preparing a micro-dosing unit containing a coating mixture which is not in contact with a gaseous phase,
- c) coating of the catheter balloon with the coating mixture using the micro-dosing unit.
A method for treatment and prophylaxis of vascular diseases in a individual, the method comprising
- administering to the individual at least one hydrophilic low molecular weight active substance in the form of a sparingly water soluble salt or as a sparingly water soluble acid or a sparingly water soluble base.
Dependencies are inferred from the claim text.