Process for preparing antiviral compound
AssigneeAbbott Laboratories
InventorsJean-Christophe Califano, James J. Napier
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Abstract
This invention is directed to: (a) processes for preparing a compound and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b) intermediates useful for the preparation of the compound and salts; (c) pharmaceutical compositions comprising the compound or salts; and (d) methods of use of such compositions.
Claims20
A process for preparing (E)-N-(4-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide (compound I) or a salt thereof, wherein the process comprises:
- reducing N-(4-((3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)ethynyl)phenyl)methanesulfonamide (compound 6):
A compound or salt thereof, wherein the compound corresponds in structure to the following formula:
A compound or salt thereof, wherein the compound corresponds in structure to the following formula:
A compound or salt thereof, wherein the compound corresponds in structure to the following formula:
A compound or salt thereof, wherein the compound corresponds in structure to the following formula:
Dependencies are inferred from the claim text.