Derivatives of heteroaryl-alkylcarbamates, methods for their preparation and use thereof as fatty acid amido hydrolase enzyme inhibitors

A compound according to the formula (I):

• wherein A is selected from the group consisting of X, Y and Z;
• wherein
• X represents a methylene group optionally substituted by one or two C1-6-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-3-alkylene groups;
• Y represents either a C2-alkenylene group optionally substituted by one or two C1-6-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-3-alkylene groups;
• or a C2-alkynylene group;
• Z represents a group of formula:
• m represents an integer ranging from 1 to 5;
• p and q represent integers and are defined such that p+q is a number ranging from 1 to 5;
• n represents an integer ranging from 1 to 7;
• R1 represents an R2 group optionally substituted by one or more R3 and R4 groups;
• R2 represents a group chosen from imidazolyl, oxazolyl, pyrazolyl, isoxazolyl, oxadiazolyl, naphthyl, quinolinyl, isoquinolinyl, 2oxo-3,4-dihydroquinolinyl, dihydroisoquinolinyl, ndolyl, benzimidazolyl, and pyrrolopyridyl,
• R3 represents a group chosen from halogen atoms, cyano, nitro, C1-6-alkyl, C3-7-cycloalkyl, C1-6-alkoxy, hydroxyl, C1-6—S-alkyl, C1-6-fluoroalkyl, C1-6-fluoroalkoxy, C1-6-fluorothioalkyl, NR5R6, NR5COR6, NR5CO2R6, NR5SO2R6, COR5, CO2R5, CONR5R6, SO2R5, SO2NR5R6, —O—(C1-3-alkylene)-O— and phenyl group, the phenyl group optionally being substituted by one or more halogen atoms;
• R4 represents a group chosen from phenyl, phenyloxy, benzyloxy, naphthyl, pyridyl, pyrimidinyl, pyridazinyl and pyrazinyl groups;
• it being possible for the R4 group or groups to be substituted by one or more R3 groups which are identical to or different from one another;
• R5 and R6 represent, independently of one another, a hydrogen atom or a C1-6-alkyl group or, with the atom or atoms which carry them, form a ring chosen from the group consisting of azetidinyl, pyrrolidinyl, piperidinyl, morpholinyl, thiomorpholinyl, azepinyl, and piperazinyl, this ring optionally being substituted by a C1-6-alkyl or benzyl group;
• R7 represents a hydrogen atom or a C1-6-alkyl group, and
• R8 represents a hydrogen atom or a C1-6-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-3-alkylene group;
• or a salt thereof.