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US 2011/0237522 A1Published application
Neutral nanotransporters
AssigneeRXi Pharmaceuticals Corporation
InventorsAnastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, Michelle Miller, Karen G. Bulock
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Abstract
Neutral lipid formulations for nucleic acid delivery are provided according to the invention. The neutral lipid formulations include hydrophobically modified polynucleotides and fat mixtures. Methods of using the neutral lipid formulations are also provided.
Claims29
A composition comprising:
- a hydrophobic modified polynucleotide;
- a neutral fatty mixture;
- and
- optionally a cargo molecule,
- wherein the hydrophobic modified polynucleotide and the neutral fatty mixture forms a micelle.
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Dependencies are inferred from the claim text.