Methods for Treating Bleeding Disorders Using Sulfated Polysaccharides
AssigneesBaxter Healthcare S.A., Baxter International Inc.
InventorKirk W. Johnson
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Abstract
Methods for treating bleeding disorders using non-anticoagulant sulfated polysaccharides (NASPs) as procoagulants are disclosed. NASPs can be administered as single agents, or in combination with one another, or with other medications (such as factors VII, VIII and IX) to promote hemostasis. In particular, the use of NASPs in treatment of bleeding disorders, including congenital coagulation disorders, acquired coagulation disorders, and trauma induced hemorrhagic conditions is described.
Claims23
1-26. (canceled)
A composition comprising:
- a procoagulant amount of a non-anticoagulant sulfated polysaccharide (NASP);
- and
- one or more pharmaceutically acceptable excipients;
- wherein the composition is in unit dosage form.
A method of enhancing blood coagulation in a subject, the method comprising:
- administering to the subject a procoagulant amount of a non-anticoagulant sulfated polysaccharide (NASP) in a manner sufficient to enhance blood coagulation in the subject.
Dependencies are inferred from the claim text.