Immobilization substrate and method for producing the same
AssigneesFUJIFILM Corporation, The University of Tokyo
InventorsKoichi Minami, Hirohiko Tsuzuki, Hiroshi Ueda, Masaki Ihara
Life of this patent
Estimating the term…
Abstract
An antibody-fragment-immobilizing substrate includes a substrate and at least one set of antibody fragments, wherein the antibody fragments of each set includes at least two types of separate antibody fragments that are capable of recognizing one type of antigen and that are independently immobilized on the substrate in a positional relationship that allows each of the antibody fragments in one set to bind to the same antigen.
Claims12
An antibody-fragment-immobilizing substrate, comprising a substrate and at least one set of antibody fragments,
- wherein the antibody fragments of each set includes at least two types of separate antibody fragments that are capable of recognizing one type of antigen and that are independently immobilized on the substrate in a positional relationship that allows each of the antibody fragments in one set to bind to the same antigen.
A method for producing an antibody-fragment-immobilizing substrate comprising:
- contacting separate antibody fragments of at least two types that are capable of recognizing one type of antigen with the antigen to form a complex whereby each of the antibody fragments binds to the antigen;
- immobilizing the complex on a substrate via the antibody fragments in the complex;
- and
- removing the antigen from the complex to obtain the antibody-fragment-immobilizing substrate,
- wherein the antibody fragments are independently immobilized on the substrate in a positional relationship that allows each of the antibody fragments to bind to the same antigen.
Dependencies are inferred from the claim text.