Pharmaceutical product for up-dosing of allergy vaccine

A method for up-dosing in connection with allergy vaccination, comprising administering a composition comprising an allergen extract of a naturally occurring allergen and aluminium hydroxide as adjuvant, wherein said composition is either contained in one unit with one concentration of allergen or is contained in two or more separate units with different concentrations of allergen, characterized in that the administration is 4, 5, or 6 subcutaneous injections with increasing amount of allergen and with intervals between the injections flexible ranging from 4 to 7 days and wherein the maximal dose of the up-dosing phase comprises aluminium hydroxide in an amount corresponding to 0.3 to 0.8 mg aluminium ion per dose and wherein the ratio of allergen to aluminium ion is the same throughout the up-dosing phase and the maintenance phase.