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US 2011/0213001 A1Published application
Pharmaceutical compositions
AssigneeKeio University
InventorsKazuo Umezawa, Yuichi Ishikawa, Shigeru Nishiyama, Miyuki Tachibana, Ayumi Kaneda
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Abstract
The object of the present invention is to provide a pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB. The pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-κB contains DTCM glutarimide of the Formula (I) as an effective ingredient, thereby being able to inhibit nitric oxide (NO) production and prostaglandin production.
Claims13
A composition comprising an effective amount of the compound of Formula (I):
- wherein n is an integer of 1 to 24.
A compound of the Formula (I):
- wherein n is an integer of 6 to 18.
Dependencies are inferred from the claim text.