Topical antiviral formulations
AssigneesConrad, International Partnership for Microbicides, Inc.
InventorTerrence C. Dahl
Life of this patent
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Abstract
The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.
Claims12
A method for the prevention of the symptoms or effects of an HIV infection in an infected animal which comprises administering to said animal a prophylactically effective amount of a topical formulation comprising an effective amount of an NRTI in combination with a pharmaceutically acceptable vehicle.
A pharmaceutical formulation comprising an NRTI and a pharmaceutically acceptable medium suitable for topical application.
A pharmaceutical formulation comprising [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir) or a physiologically functional derivative thereof and a pharmaceutically acceptable medium suitable for topical application.
Dependencies are inferred from the claim text.