Malva mosaic virus and virus-like particles and uses thereof
AssigneeUniversite Laval
InventorDenis Leclerc
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Abstract
The immunogenic properties of the potexvirus MaI va mosaic virus (MaMV) and virus-like particles (VLPs) comprising the coat proteins of MaMV are disclosed VLPs prepared from MaMV coat proteins, methods of preparing the VLPs, MaMV coat protein polypeptides and polynucleotides encoding the coat protein are taught. Further, immunogenic compositions comprising MaMV or a VLP comprising the MaMV coat protein alone or in combination with one or more antigens and the use of said compositions to vaccinate and/or induce an immune response in an animal are also taught.
Claims49
An immunogenic composition comprising Malva mosaic virus (MaMV) or a virus-like particle (VLP) comprising MaMV coat protein and a pharmaceutically acceptable carrier.
A method of vaccinating an animal against a disease, disorder or infection comprising administering to said animal an effective amount of immunogenic composition comprising Malva mosaic virus (MaMV) or a virus-like particle (VLP) comprising MaMV coat protein and one or more antigens.
-29. (canceled)
A virus-like particle (VLP) comprising Mavia mosaic virus (MaMV) coat protein.
A method of preparing a virus-like particle (VLP), said method comprising the step of expressing a Malva mosaic virus (MaMV) coat protein in a host cell.
A fusion protein comprising a Malva mosaic virus (MaMV) coat protein fused to an antigen.
(canceled)
Dependencies are inferred from the claim text.