Proteinases destroy cancer tumor's solid structure and kill cancer cells locally
AssigneeBiomedicure
InventorYONG QIAN
Life of this patent
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Abstract
A proteinase therapy has been invented to eliminate solid tumors by destroying tumors' solid structure and killing cancer cells by cleaving vital extracellular matrix proteins C-terminally, N-terminally or both with cell membrane intact and limited adverse effects. The micro-scale intratumoral proteinase K therapy is tumor specific but not cancer type specific. Proteinase K therapy can be operated on multiple tumors on multiple occasions, if necessary. It may be employed to eliminate any solid tumor to prolong a cancer patient's life span.
Claims16
Use of a proteinase for treating a tumor, wherein the protease has a substrate specificity that includes extracellular matrix protein (ECMP) and/or the extracellular part of a transmembrane protein (EPTMP) of cancer cells while keeping cell membranes of the cancer cells intact before the cancer cells undergo arrest, necrosis or apoptosis.
Use of a proteinase for manufacturing a medicament for treating a tumor, wherein the protease that cleaves extracellular matrix protein (ECMP) and/or the extracellular part of a transmembrane protein (EPTMP) of cancer cells while keeping cell membranes of the cancer cells intact before the cancer cells undergo arrest, necrosis or apoptosis.
3-11. (canceled)
A pharmaceutical composition formulated for administration both in and around a tumor, comprising a proteinase that cleaves the extracellular matrix protein (ECMP) and/or the extracellular part of a transmembrane protein (EPTMP) of cancer cells while keeping cell membranes of the cancer cells intact before the cancer cells undergo arrest, necrosis or apoptosis.
Dependencies are inferred from the claim text.