Individualized cancer treatments
AssigneesDuke University, University of South Florida
InventorsJohnathan M. Lancaster, Joseph R. Nevins
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AssigneesDuke University, University of South Florida
InventorsJohnathan M. Lancaster, Joseph R. Nevins
Estimating the term…
The invention provides for compositions and methods for predicting an individual's responsitivity to cancer treatments and methods of treating cancer. In certain embodiments, the invention provides compositions and methods for predicting an individual's responsitivity to chemotherapeutics, including platinum-based chemotherapeutics, to treat cancers such as ovarian cancer. Furthermore, the invention provides for compositions and methods for predicting an individual's responsivity to salvage therapeutic agents. By predicting if an individual will or will not respond to platinum-based chemotherapeutics, a physician can reduce side effects and toxicity by administering a particular additional salvage therapeutic agent. This type of personalized medical treatment for ovarian cancer allows for more efficient treatment of individuals suffering from ovarian cancer. The invention also provides reagents, such as DNA microarrays, software and computer systems useful for personalizing cancer treatments, and provides methods of conducting a diagnostic business for personalizing cancer treatments.
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A method of identifying whether an individual will benefit from the administration of a cancer therapeutic comprising:
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A method of treating a human individual with ovarian cancer comprising:
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Dependencies are inferred from the claim text.