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US 2010/0303849 A1Published application
Lipidated Vaccine against Dengue Virus Infection
AssigneeNational Health Research Institutes
InventorsHsin-Wei Chen, Chih-Hsiang Leng, Shih-Jen Liu, Pele Choi-Sing Chong
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Abstract
Disclosed are immunogenic composition, fusion proteins, and related methods for inducing immune response to dengue virus infection.
Claims20
An isolated fusion protein, comprising
- a first segment having a lipidating sequence and
- a second segment having the sequence of a dengue viral protein fragment, wherein the first segment is located at the N-terminus to the second segment in the fusion protein.
An isolated antibody that selectively binds to a peptide comprising a sequence selected from the group consisting of SEQ ID NOs:
- 6 and 23-26.
Dependencies are inferred from the claim text.