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OwnerBelinda Cairns, Ruihuan Chen +11inventors
InventorsBELINDA CAIRNS, Ruihuan Chen, Gretchen Frantz, Kenneth J. Hillan, Hartmut Koeppen, Heidi S. Phillips, Paul Polakis, Susan D. Spencer, Victoria Smith, P. Mickey Williams, Thomas D. Wu, Zemin Zhang, Mark Sliwkowski
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The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
A method of inhibiting growth of a cell expressing TAT188, the method comprising contacting the cell with an antibody comprising in a corresponding complementary determining region (CDR) an amino acid sequence having the amino acid sequence of all six of the CDRs in the specific order as found in the antibody secreted by a hybridoma selected from the group consisting of 3B5.1 (ATCC Accession Number PTA-6193), 12B9.1 (ATCC Accession Number PTA-6194), and 12G12.1 (ATCC Accession Number PTA-6195).
A method of detecting the level of TAT188 polypeptide expressed in a test cell relative to a control cell, the method comprising:
A method of detecting the level of TAT188 polypeptide or a polypeptide having at least 80% sequence identity to the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.