Content of the essential amino acids lysine and methionine in algae and cyanobacteria for improved animal feed
AssigneeTransAlgae Ltd
InventorsShai Ufaz, Jonathan Gressel
Life of this patent
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Abstract
This disclosure provides a method to improve lysine and methionine content of algae and cyanobacteria through genetic modification in combination with modified expression of high lysine and methionine proteins as sinks for the amino acids. The method of this disclosure is specifically useful in animal feed production.
Claims23
A method to produce improved animal feed, said method comprising the steps of:
- a. Genetically modifying alga or cyanobacterium methionine and/or lysine biosynthesis to upregulate production of methionine and/or lysine;
- b. Transforming the alga or cyanobacterium with a nucleotide sequence encoding a high methionine and/or lysine protein for a sink of the upregulated methionine and/or lysine;
- c. Cultivating the alga or cyanobacterium in an axenic culture;
- d. Harvesting cultured algae or cyanobacteria;
- and
- e. Providing the algae or cyanobacteria for animal feed.
A transgenic algae or cyanobacterium having an upregulated biosynthesis of methionine and/or lysine.
Animal feed composition comprising transgenic algae or cyanobacteria having a modified biosynthesis of methionine and/or lysine and expressing recombinant protein with high lysine and/or methionine content.
Animal feed composition comprising recombinant protein produced in algae or cyanobacteria.
Dependencies are inferred from the claim text.