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US 2010/0249026 A1Published application
Albumin fusion proteins
AssigneeHuman Genome Sciences, Inc.
InventorsCRAIG A. ROSEN, WILLIAM A. HASELTINE
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AssigneeHuman Genome Sciences, Inc.
InventorsCRAIG A. ROSEN, WILLIAM A. HASELTINE
Estimating the term…
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.
-29. (canceled)
An albumin fusion protein comprising a Therapeutic protein:X fused to an albumin polypeptide.
An albumin fusion protein comprising a follicle stimulating hormone (FSH) alpha subunit polypeptide, or a variant or fragment thereof, fused to an albumin polypeptide, wherein said variant or fragment of the FSH alpha subunit polypeptide has FSH alpha subunit activity, and wherein said albumin polypeptide is selected from:
A method of extending the shelf-life of follicle stimulating hormone (FSH) alpha subunit polypeptide, or a fragment or variant thereof, comprising the step of fusing the FSH alpha subunit polypeptide, or fragment or variant thereof, to an albumin polypeptide, wherein said variant or fragment of FSH alpha subunit polypeptide has FSH alpha subunit activity, and wherein said albumin polypeptide is selected from:
Dependencies are inferred from the claim text.