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US 2010/0247594 A1Published application
Delivery of dry formulations of octreotide
AssigneeEndo Pharmaceuticals Solutions Inc.
InventorsPetr KUZMA, Stefanie Decker
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Abstract
Methods and devices are described for delivering octreotide to a patient, comprising implanting a controlled release composition for delivering octreotide, wherein the composition does not require hydration prior to implantation, and wherein the composition optionally comprises a release agent.
Claims18
A method of delivering octreotide to a subject with a substantially zero-order release profile over an extended period of time, but no less than about six months, the method comprising:
- subcutaneously implanting in the subject at least one implantable device;
- wherein:
- the at least one implantable device comprises
- a composition comprising octreotide encased in a hydrophilic polymer;
- and
- the implantable device is implanted in a dry state, such that the subject receives on a daily basis over a period of at least about six months dose amounts of octreotide, which are effective to treat the subject.
3 more elements
Dependencies are inferred from the claim text.