Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains
AssigneesAventis Pasteur Limited, Institut National De La Sante Et De La Recherche Medicale (Inserm)
InventorsLuc AUJAME, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
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Abstract
The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
Claims10
A polypeptide specific to the pathogenic strains of the genus Neisseria or an antigenic fragment thereof, wherein said polypeptide has an amino acid sequence that is at least 75% identical to SEQ ID NO:
- 8 or SEQ ID NO:
- 53, provided that said polypeptide is not encoded by a nucleic acid having a sequence of SEQ ID NO:
- 74A or of SEQ ID NO:
- 95A.
A pharmaceutical composition comprising a pharmaceutically acceptable vehicle in combination with a polypeptide specific to the pathogenic strains of Neisseria or an antigenic fragment thereof, wherein said polypeptide has an amino acid sequence that is at least 75% identical to SEQ ID NO:
- 8 or SEQ ID NO:
- 53, provided that said polypeptide is not encoded by a nucleic acid having a sequence of SEQ ID NO:
- 74A or of SEQ ID NO:
- 95A.
Dependencies are inferred from the claim text.